This study aims to identify the factors that influence the lending behavior of commercial banks in Nepal. The study has used a combination of descriptive and causal relationship research design and taken major ten commercial banks of Nepal sample over a ten-year period (2011/12-2020/21 A.D.). The results of the study show that bank size, interest rate spread, and exchange rate has a positive and significant impact on commercial bank lending in Nepal, while GDP growth rate and inflation rate has a negative and significant impact. In contrast, the cash reserve ratio has an insignificant and negative impact on lending. Based on these findings, the researcher recommended that policies should be developed to support the growth of commercial banks and encourage lending, with a focus on improving interest rate spreads and increasing the size of banks.